Genetic epidemiology of essential hypertension

Association of CALCA genetic polymorphism with essential hypertension.

BACKGROUND Calcitonin gene-related peptide (CGRP) is the predominant neurotransmitter in capsaicin-sensitive sensory nerves. Participation of CGRP in hypertension is one of the most extensively studied topics in the field. There is growing evidence to the effect that CGRP is associated with essential hypertension (EH). The aims of this study were to pinpoint whether single nucleotide polymorphi...

Discovering the genetic basis of essential hypertension: hypes and hopes.

Are Genetic factors really predisposing for essential hypertension?

Sodium-potassium cotransport activity as genetic marker in essential hypertension.

Sodium-potassium cotransport activity is thought to be defective in essential hypertension and could be a useful genetic marker for susceptibility to essential hypertension. In this study cotransport activity in subjects with hypertension was compared with that in normotensive controls. The effects of ethnic differences, environment, and antihypertensive drugs were also studied. Mean cotranspor...

Epidemiology of hypertension.